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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
33.64
Human Site:
T112
Identified Species:
52.86
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
T112
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
Chimpanzee
Pan troglodytes
XP_523815
451
50966
I86
V
N
R
G
P
E
K
I
R
P
E
C
F
E
L
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
T112
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
Dog
Lupus familis
XP_537702
525
59107
T112
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
T112
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
Rat
Rattus norvegicus
P67999
525
59113
T112
V
F
Q
V
R
K
V
T
G
A
N
T
G
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
M86
M
K
V
L
K
K
A
M
I
V
R
N
A
K
D
Chicken
Gallus gallus
P18652
752
84421
T101
V
F
L
V
R
K
I
T
P
P
D
S
N
H
L
Frog
Xenopus laevis
P10666
629
71268
N88
K
I
T
P
P
D
A
N
Q
L
Y
A
M
K
V
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
M88
V
F
L
V
R
K
L
M
G
P
D
A
G
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
T282
V
F
L
V
R
K
L
T
R
H
D
A
G
K
L
Honey Bee
Apis mellifera
XP_395876
456
51514
T90
V
F
Q
V
R
K
I
T
G
N
D
S
G
T
I
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
R125
V
F
L
V
R
K
V
R
G
R
D
S
G
H
V
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
T93
V
F
Q
V
R
K
T
T
G
K
D
S
G
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
T95
N
K
L
T
L
R
E
T
E
D
S
V
D
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
13.3
40
6.6
46.6
N.A.
53.3
66.6
53.3
73.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
33.3
66.6
13.3
73.3
N.A.
73.3
86.6
73.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
14
0
0
34
0
20
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
0
7
40
0
7
0
7
% D
% Glu:
0
0
0
0
0
7
7
0
7
0
7
0
0
7
0
% E
% Phe:
0
74
0
0
0
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
60
0
0
0
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
14
0
% H
% Ile:
0
7
0
0
0
0
14
7
7
0
0
0
0
0
47
% I
% Lys:
7
14
0
0
7
80
7
0
0
7
0
0
0
60
0
% K
% Leu:
0
0
34
7
7
0
14
0
0
7
0
0
0
7
27
% L
% Met:
7
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% M
% Asn:
7
7
0
0
0
0
0
7
0
7
34
7
7
0
0
% N
% Pro:
0
0
0
7
14
0
0
0
7
20
0
0
0
0
0
% P
% Gln:
0
0
47
0
0
0
0
0
7
0
0
0
0
7
0
% Q
% Arg:
0
0
7
0
74
7
0
7
14
7
7
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
7
27
0
0
0
% S
% Thr:
0
0
7
7
0
0
7
67
0
0
0
34
0
7
0
% T
% Val:
80
0
7
74
0
0
40
0
0
7
0
7
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _